Page 5 de l'historique des matchs du joueur de tennis: Retrouvez ici la totalité des matchs et tournois joués par John Isner.
101 matchs enregistrés.
| 31/07/2021 | Truist Atlanta Open - Atlanta | John Isner vs. Christopher O'Connell |
| 29/07/2021 | Truist Atlanta Open - Atlanta | John Isner vs. Jack Sock |
| 25/07/2021 | Truist Atlanta Open - Atlanta | John Isner vs. Jeff Wolf |
| 24/07/2021 | Abierto Mexicano de Tenis Mifel - Los Cabos | Brandon Nakashima vs. John Isner |
| 23/07/2021 | Abierto Mexicano de Tenis Mifel - Los Cabos | Alex Bolt vs. John Isner |
| 21/07/2021 | Abierto Mexicano de Tenis Mifel - Los Cabos | Evgeny Donskoy vs. John Isner |
| 28/06/2021 | Wimbledon - London | Yoshihito Nishioka vs. John Isner |
| 04/06/2021 | French Open - Paris | Stefanos Tsitsipas vs. John Isner |
| 02/06/2021 | French Open - Paris | Filip Krajinovic vs. John Isner |
| 30/05/2021 | French Open - Paris | Sam Querrey vs. John Isner |
| 07/05/2021 | Mutua Madrid Open - Madrid | Dominic Thiem vs. John Isner |
| 06/05/2021 | Mutua Madrid Open - Madrid | John Isner vs. Andrey Rublev |
| 05/05/2021 | Mutua Madrid Open - Madrid | Roberto Bautista Agut vs. John Isner |
| 03/05/2021 | Mutua Madrid Open - Madrid | John Isner vs. Miomir Kecmanovic |
| 30/03/2021 | Miami Open - Miami | John Isner vs. Roberto Bautista Agut |
| 28/03/2021 | Miami Open - Miami | Felix Auger Aliassime vs. John Isner |
| 26/03/2021 | Miami Open - Miami | Mackenzie Mcdonald vs. John Isner |
| 18/03/2021 | Abierto Mexicano Telcel - Acapulco | Stefanos Tsitsipas vs. John Isner |
| 15/03/2021 | Abierto Mexicano Telcel - Acapulco | John Isner vs. Salvatore Caruso |
| 11/01/2021 | Delray Beach Open - Delray Beach | Sebastian Korda vs. John Isner |