Reilly Opelka leads 3 to 1 over 4 singles meetings since 2021. Last meeting on 26/08/2024 at U.S. Open - New York.
| Date | Tournament | Round | Surface | Winner | Score |
|---|---|---|---|---|---|
| 26/08/2024 | U.S. Open - New York | Round 1 | hard | Musetti | 7-6(3) 1-6 6-1 7-5 |
| 12/03/2022 | BNP Paribas Open - Indian Wells | Round 2 | hard | Opelka | 6-1 6-4 |
| 01/09/2021 | U.S. Open - New York | Round 2 | hard | Opelka | 7-6(1) 7-5 6-4 |
| 11/05/2021 | Internazionali BNL d'Italia - Rome | Round 2 | clay | Opelka | 6-4 6-4 |
| hard | Opelka 2 - 1 Musetti |
| clay | Opelka 1 - 0 Musetti |
| 2024 | Opelka 0 - 1 Musetti |
| 2022 | Opelka 1 - 0 Musetti |
| 2021 | Opelka 2 - 0 Musetti |
90 wins, 85 losses since 2021 (51.4%).
Last matches: D D D V V
232 wins, 149 losses since 2021 (60.9%).
Last matches: V D V V D
Reilly Opelka leads 3 to 1 over 4 singles meetings since 2021.
On 26/08/2024, at U.S. Open - New York (Round 1): Lorenzo Musetti won 7-6(3) 1-6 6-1 7-5.